KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
23.33
Human Site:
S393
Identified Species:
36.67
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
S393
K
K
K
T
H
H
C
S
E
E
K
E
D
E
D
Chimpanzee
Pan troglodytes
XP_527529
607
69328
S508
K
K
K
T
R
H
C
S
E
E
K
E
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
S393
K
K
K
T
R
H
C
S
E
E
K
E
D
E
D
Dog
Lupus familis
XP_541147
492
57155
S393
K
K
K
T
R
H
C
S
E
E
K
E
D
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
S393
K
K
K
T
R
H
C
S
E
E
K
E
D
E
E
Rat
Rattus norvegicus
NP_001101927
357
40656
I259
T
D
E
D
L
E
I
I
F
S
R
F
G
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
S389
K
K
K
K
H
S
H
S
D
E
E
E
D
D
K
Chicken
Gallus gallus
XP_419663
478
55881
S379
E
E
S
Q
T
S
Q
S
H
V
A
K
K
Q
K
Frog
Xenopus laevis
Q6GLX7
477
54856
Y371
Y
L
K
E
K
E
K
Y
E
E
V
R
K
K
N
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
V355
K
L
A
L
K
D
K
V
K
S
K
Q
D
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
N428
Q
N
E
S
V
R
E
N
S
N
R
E
R
N
R
Honey Bee
Apis mellifera
XP_001121334
512
60307
N386
H
E
Y
R
K
N
D
N
K
N
N
S
E
C
S
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
K329
Q
N
Y
K
Y
K
P
K
S
Q
Q
Q
E
A
P
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
R433
S
E
S
E
D
G
R
R
R
K
R
S
Q
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
E390
Y
Q
M
V
H
G
V
E
D
L
K
G
R
H
D
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
0
N.A.
53.3
6.6
20
20
N.A.
6.6
0
0
0
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
13.3
N.A.
73.3
33.3
33.3
33.3
N.A.
40
33.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
34
0
0
0
0
0
0
7
0
% C
% Asp:
0
7
0
7
7
7
7
0
14
0
0
0
47
7
34
% D
% Glu:
7
20
14
14
0
14
7
7
40
47
7
47
14
34
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
14
0
0
0
0
0
7
7
7
0
% G
% His:
7
0
0
0
20
34
7
0
7
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% I
% Lys:
47
40
47
14
20
7
14
7
14
7
47
7
14
7
14
% K
% Leu:
0
14
0
7
7
0
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
14
0
0
0
7
0
14
0
14
7
0
0
7
7
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
7
% P
% Gln:
14
7
0
7
0
0
7
0
0
7
7
14
7
7
0
% Q
% Arg:
0
0
0
7
27
7
7
7
7
0
20
7
14
0
14
% R
% Ser:
7
0
14
7
0
14
0
47
14
14
0
14
0
7
7
% S
% Thr:
7
0
0
34
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
7
0
7
7
0
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
14
0
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _